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Once all four doses are used, the pen should be safely discarded as directed

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However, the absence of known interactions may partly reflect the limited scope of formal studies on NAD+ therapy, so this lack of interactions should be interpreted with caution

Both on demand apomorphine formulations were developed to overcome the limitations of oral apomorphine, which has a short half-life and undergoes extensive metabolism in the gastrointestinal tract, and both have demonstrated efficacy in clinical trials [8]